Endocrine Abstracts

GH is used primarily to increase adult height in short children with GHD/NSD with little knowledge about the impact of GH on health-related quality of life (HRQoL). Therefore this study was carried out to evaluate HRQoL in adult patients with childhood onset GHD/NSD at the end of GH therapy.HrQoL was measured by patient self-report using two generic questionnaires, SF36 and NHP. Patient data were compared to representative norm data. Clinical data as wel...

In children whose height is substantially below norms, behavioural and emotional problems can be experienced. When evaluating the outcomes of treatments or making treatment decisions, health related quality of life (HrQoL) should be taken into consideration. At present, no standardised HrQoL instrument for short stature youth exists. Through consensus building in five countries, the objective of this study was to develop and psychometrically test a growth-related HrQoL instrum...

Background: About 3% of all children are short statured. Clinically GH deficiency (GHD) or idiopathic short stature (ISS) is frequently diagnosed. GH (GH−) treatment, which is primarily indicated for GHD patients, is provided not only to increase height, but also to improve psychological functioning and raise health related quality of life. The present study examines these psychosocial outcomes in young German patients and their parents, and analyzes differences accordin...